Finding the underlying mechanisms responsible for Triple Negative Breast Cancer
|Type of institution|
McMaster University, Main Street West, Hamilton, ON, Canada
|I have a knowledge mobilization grant.|
|Health care and social assistance|
Introduce your team
My name is Lyndsay Rayner and I am a master’s student in the Department of Biology at McMaster University.
Describe your research
The main focus of my work in the lab is we look at a protein called kaiso which is a transcription factor which has shown to be highly expressed in a subtype of breast cancer called triple negative breast cancer. It is a highly aggressive and metastatic breast cancer and it’s typically diagnosed in women of African ancestry compared to Caucasian women.
It’s been speculated that there’s a genetic predisposition for a woman of African ancestry to have this subtype of breast cancer. My work focuses on examining the link between kaiso and this subtype of breast cancer.
Explain its significance
This work is very important because triple negative breast cancer does have really poor mortality rates compared to other subtypes of breast cancer. So finding the underlying mechanisms responsible for this type of breast cancer would have great clinical significance for patients that are suffering from this disease